Endocrine Disorders that Cause Diabetes

Abstract

Endocrine disorders are a scientific group of
conditions that affect the day-to-day functioning
of the endocrine system, which is responsible for
producing and regulating hormones in the body.
Many endocrine problems can lead to the
development of diabetes, a metabolic disorder
characterized by persistently high blood sugar
levels. Excess cortisol can cause insulin resistance,
which causes an increase in blood sugar levels,
and eventually leads to diabetes. Another disease
is acromegaly which is caused by an
overproduction of increased hormones. An
extended hormone boom stage can lead to insulin
resistance in the long term, contributing to an
increase in diabetes. Polycystic ovary syndrome
(PCOS) is an endocrine disease commonly
associated with insulin resistance and diabetes.
PCOS is characterized by an imbalance of
hormones, especially androgens. This imbalance
can impair insulin signaling, especially insulin
resistance, and the subsequent development of
diabetes. Hypothyroidism, which is characterized
by low thyroid hormone levels, can lead to insulin
resistance and impaired insulin secretion. In
contrast, hyperthyroidism, which is characterized
by overproduction of thyroid hormone, can
increase glucose metabolism and lead to diabetes
in susceptible individuals. In addition, tumors of
the endocrine system, including insulinomas and
glucagonomas, can cause atypical insulin
production and release, leading to hypoglycemia
and hyperglycemia, respectively