Comparative Study of Cancer Biology in Humans and Animals
DOI:
https://doi.org/10.59890/w5z0fv38Keywords:
Cancer, Comparative Study, Biology, Humans, AnimalsAbstract
Cancer is a major cause of mortality globally, affecting humans and animals equally. Inspite of this relevant advances in cancer research, the underlying biology of cancer remains poorly comprehend. This research aimed to explore the similarities and differences in cancer biology between humans and animals. Numerous studies on the genetic basis of cancer have been carried out since it has long been thought to be a hereditary disease. These paper give compelling evidence for the genetic basis of cancer, such as the idea that the disease develops as a result of a build-up of genetic mutations, epigenetic modifications, and variations in key genes that control cell development. Relevant information about the genetic mechanisms controlling the development, spread, metastasis, reaction to treatment, and drug resistance of cancer have been provided by genetic models of cancer growth. Our results indicate that while there are similarities in cancer pathology and genetics, there are also distinct differences in tumor growing, progression, and response to treatment. These findings have relevant impactation for the development of novel cancer therapies and highlights the need for further research into the comparative biology of cancer
References
A 2021 study published in medicine explored the relationship between cancer, bacteria, and immunity, highlighting the importance of microbiome in carcinogenesis. The study discussed the use of germ free animals to investigate the role of bacteria in cancer development
Research published in Cancer in 2021 delved into proteomics, personalized medicine, and cancer, discussing the importance of proteomics in understanding cancer biology. The study highlighted various proteomic techniques, including iTRAQ and TMT, used to identify bio markers for early cancer detection.
A 2024 study published in Biomedicines examined the metabolic diversity of ovarian cancer cells using metabolics, revealing distinct metabolic groups and potential therapeutic targets.
These studies demonstrate the ongoing efforts to understand cancer biology through comparative research in humans and animals, leveraging cutting - edge technologies like proteomics and metabolics.
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