Gender-Based Comparative Study of the Influence of Cola Nitida on the Urinary Flow Rate of Humans

Igbinovia Edokpolor Nestor; Ohiwerei Wisdom Omogbai; Edebiri Ogbemudia; Blackie Okosun; Ilesanmi Johnson Opeyemi

doi:10.59890/j7e2c718

Authors

Igbinovia Edokpolor Nestor Ambrose Alli University Author
Ohiwerei Wisdom Omogbai Mudiame University Author
Edebiri Ogbemudia Ambrose Alli University Author
Blackie Okosun Ambrose Alli University Author
Ilesanmi Johnson Opeyemi Imo State University Author

DOI:

https://doi.org/10.59890/j7e2c718

Keywords:

Cola Nitida, Urinary Flow Rate, Sweat Chamber

Abstract

This study investigated the impact of Cola nitida consumption on urinary flow rate in males and females. A total of 60 subjects (30 males and 30 females), aged 18–28 years and unaccustomed to Cola nut consumption, were recruited. Participants were categorized into three body weight groups: underweight, normal weight, and overweight. Individuals with hypertension, renal disorders, or cardiopulmonary conditions were excluded. The experiment was conducted under three environmental conditions: normal chamber temperature (27°C, 70% RH), raised chamber temperature (37°C, 90% RH), and normal chamber temperature with exercise, where subjects cycled on a bicycle ergometer at 750J/min for 20 minutes. Before exposure to these conditions, each subject provided a urine sample to measure baseline urinary volume. Following 20 minutes in the sweat chamber, another urine sample was collected to determine the actual urinary output over the given period. Urinary flow rate was then calculated. Each subject ingested Cola nitida (0.5g/kg body weight) as a bolus, followed by 50ml of deionized water. A 90-minute rest period was observed before the subjects were placed in the sweat chamber. The results revealed significant (P<0.05) decreases in urinary flow rate among female underweight subjects under normal conditions, as well as in overweight females across all experimental conditions (normal, raised temperature, and exercise) compared to their male counterparts. These findings suggest a possible gender-based physiological variation in response to Cola nitida, potentially influenced by differences in hormonal regulation, metabolic activity, and fluid balance mechanisms

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